SEP-363856 hydrochloride
CAS No. 1310422-41-3
SEP-363856 hydrochloride ( SEP-856 hydrochloride )
Catalog No. M22443 CAS No. 1310422-41-3
SEP-363856 hydrochloride is an agent of orally active and CNS active psychotropic with a unique, non-D2/5-HT2A mechanism of action, exerts its antipsychotic-like effects, has the potential to treatment of schizophrenia. SEP-856 (10μM) specifically inhibits α2A, α2B, D2, 5-HT1A, 5-HT1B, 5-HT1D, 5-HT2A, 5-HT2B, 5-HT2C and 5-HT7> 50% receptor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 224 | Get Quote |
|
10MG | 374 | Get Quote |
|
25MG | 623 | Get Quote |
|
50MG | 887 | Get Quote |
|
100MG | 1197 | Get Quote |
|
500MG | 2394 | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
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Product NameSEP-363856 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionSEP-363856 hydrochloride is an agent of orally active and CNS active psychotropic with a unique, non-D2/5-HT2A mechanism of action, exerts its antipsychotic-like effects, has the potential to treatment of schizophrenia. SEP-856 (10μM) specifically inhibits α2A, α2B, D2, 5-HT1A, 5-HT1B, 5-HT1D, 5-HT2A, 5-HT2B, 5-HT2C and 5-HT7> 50% receptor.
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DescriptionSEP-363856 hydrochloride is an agent of orally active and CNS active psychotropic with a unique, non-D2/5-HT2A mechanism of action, exerts its antipsychotic-like effects, has the potential to treatment of schizophrenia. SEP-856 (10μM) specifically inhibits α2A, α2B, D2, 5-HT1A, 5-HT1B, 5-HT1D, 5-HT2A, 5-HT2B, 5-HT2C and 5-HT7> 50% receptor.SEP-856 (0.3, 1 and 10 mg/kg, i.p.) is CNS active. SEP-856 exhibits a behavioral signature similar to known antipsychotic drugs.PCP-induced hyperactivitysignificantly reduced by SEP-856 (0.3, 1 and 10 mg/kg, orally once) . Oral SEP-856 administration (1, 3 and 10 mg/kg) produces a dosedependent decrease in REM sleep, increase in latency to REM sleep and increase in cumulative wake (W) time.
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SynonymsSEP-856 hydrochloride
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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Recptor5-HT1A Receptor;5-HT1B Receptor;5-HT1D Receptor;5-HT2A Receptor;5-HT2C Receptor;5-HT7 Receptor;TAAR1
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Research Area——
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Indication——
Chemical Information
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CAS Number1310422-41-3
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Formula Weight219.73
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Molecular FormulaC9H14ClNOS
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Purity>98% (HPLC)
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SolubilityDMSO:62.5 mg/mL (284.44 mM; Need ultrasonic)
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SMILESCl.CNC[C@@H]1OCCc2ccsc12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Dedic N, et al. SEP-363856, a Novel Psychotropic Agent with a Unique, Non-D2 Receptor Mechanism of Action. J Pharmacol Exp Ther. 2019 Oct;371(1):1-14.
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